diff --git a/debian/changelog b/debian/changelog
index 9eee18b..605305b 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -1,3 +1,11 @@
+rpy2 (3.5.4-2) UNRELEASED; urgency=medium
+
+ * Remove constraints unnecessary since buster:
+ + Build-Depends: Drop versioned constraint on python3-all-dev.
+ + python3-rpy2: Drop versioned constraint on r-base-core in Depends.
+
+ -- Debian Janitor <janitor@jelmer.uk> Thu, 25 Aug 2022 18:45:51 -0000
+
rpy2 (3.5.4-1) unstable; urgency=medium
* New upstream release
diff --git a/debian/control b/debian/control
index c4dc946..6e82105 100644
--- a/debian/control
+++ b/debian/control
@@ -3,7 +3,7 @@ Section: python
Priority: optional
Maintainer: Dirk Eddelbuettel <edd@debian.org>
Standards-Version: 4.6.1
-Build-Depends: debhelper-compat (= 11), dh-python, r-base-dev (>= 4.2.1), python3-all-dev (>= 3.1.2-10~), python3-setuptools, python3-numpy-dev, python3-cffi, python3-tzlocal
+Build-Depends: debhelper-compat (= 11), dh-python, r-base-dev (>= 4.2.1), python3-all-dev, python3-setuptools, python3-numpy-dev, python3-cffi, python3-tzlocal
X-Python3-Version: >= 3.6
Vcs-Browser: https://salsa.debian.org/edd/rpy2
Vcs-Git: https://salsa.debian.org/edd/rpy2.git
@@ -11,7 +11,7 @@ Homepage: https://rpy2.github.io/
Package: python3-rpy2
Architecture: any
-Depends: ${shlibs:Depends}, ${python3:Depends}, ${misc:Depends}, python3-numpy, r-base-core (>= 3.5.0), python3-jinja2, python3-tzlocal
+Depends: ${shlibs:Depends}, ${python3:Depends}, ${misc:Depends}, python3-numpy, r-base-core, python3-jinja2, python3-tzlocal
Provides: ${python3:Provides}
Suggests: python-rpy-docs
Description: Python3 interface to the GNU R language and environment (version 2)
